The risk associated with any chemical substance depends on:

The risk associated with any chemical substance is influenced by a variety of factors that together determine its overall impact on health and safety. These factors include the inherent toxicity of the substance, the level of exposure, the duration of exposure, the route of exposure (inhalation, dermal contact, ingestion), and the susceptibility of the individual handling or encountering the substance, which can vary based on age, sex, pre-existing health conditions, and genetics.

Considering only toxicity ignores the complexities involved in real-world scenarios where exposure circumstances play a critical role. Similarly, personal attitudes or perceptions about chemicals, no matter how positive or negative, do not directly influence the measurable risk involved. Atmospheric pressure can affect the behavior of certain chemicals, but it is not a fundamental determinant of risk across all substances.

By acknowledging the multiple interrelated factors that contribute to chemical risk, it becomes clear that a comprehensive understanding of chemical safety is necessary for effective management and mitigation strategies.